Quercetin and rutin as potential agents antifungal against Cryptococcus spp

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Quercetin and rutin as potential agents antifungal against Cryptococcus spp.

Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting as cryptococcosis the immunocompromised patients. However, severe side effects have limited the utility of this drug. The aim of this study was to evaluate the antifungal effect of the combination of amphotericin B with quercetin or rutin and as a protective of citotoxic effect. Th...

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In-vitro evaluation of rutin and rutin hydrate as potential radiation countermeasure agents

Background: DNA damage is one of the major consequences of radia on exposure onto the biological systems. A series of compounds including flavanoids were found to render DNA protec on against radia on damage. In this study we elucidated the poten al of ru n and ru n hydrate to protect plasmid DNA against damage induced by irradia on. Materials and Methods: DPPH and hydroxyl radical scavenging a...

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in-vitro evaluation of rutin and rutin hydrate as potential radiation countermeasure agents

background: dna damage is one of the major consequences of radiation exposure onto the biological systems. a series of compounds including flavanoids were found to render dna protection against radiation damage. in this study we elucidated the potential of rutin and rutin hydrate to protect plasmid dna against damage induced by irradiation. materials and methods: dpph and hydroxyl radical scave...

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ژورنال

عنوان ژورنال: Brazilian Journal of Biology

سال: 2016

ISSN: 1678-4375,1519-6984

DOI: 10.1590/1519-6984.07415